The AMRF aims to create a culture of scientific discovery, evaluation, and clinical application directed by the experiences of scientists who are not bound by searching for the cure of a single disease. Programs within the AMRF are defined in broad terms, such as the Adelson Program in Neural Repair and Rehabilitation (APNRR) which seeks to manipulate the regeneration of axons in the brain, spinal cord and peripheral nerves, and the Adelson Program in Cancer Research (APCR) which seeks therapies targeted to the mechanisms that make cells malignant.
We encourage investigators to find common denominators across diseases in their genes, cells, molecules and pathways. Clinical scientists work closely with basic scientists to help focus their joint aims, milestones and best applications for therapies. Institutions are funded on the premise that a diverse group of experts who share a common vision and agree on common objectives will most efficiently allocate resources to achieve their research objectives.
Instead of funding individual experiments that cautiously advance progress, we ask investigators who receive funding to interact with peers at many institutions within the context of creative and risk-taking approaches that may yield much more than the incremental progress engendered by many funding organizations.
Our model of research calls for collaborative Programs that evolve during workshops with invited scientists from different laboratories and universities. Although we do not seek applications for funds from individual investigators or institutions outside of this approach, the Executive Director and Scientific Officers and Heads of Program Development are interested in discussing ideas for new programs suggested by potential participants. Collaborations can extend to having funded investigators interact with other foundations and with the biopharmaceutical industry.